Nuclear Hormone Receptor Targets Available

DiscoveRx offers a series of assays that measure NHR translocation and NHR/steroid co-factor interaction. These unique assays are chemiluminescent and do not require lengthy 16-24 hour compound incubations characteristic of standard reporter gene assays.

 

Technology Overview

PathHunter cell-based NHR platform


Browse Available Nuclear Hormone Receptor Targets

Listed below are the cell-based NHR targets available for screening and profiling.  Assays in the table may be sorted by column name.  Contact us if you don't see your target of interest in our list below as additional catalog cell lines may be available for screening and profiling as a custom service.
Target Gene ▲SpeciesGeneBank Accession NoNuclear TranslocationCo-Factor Protein Interaction
ARHumanNM_000044XX
ERRαHumanNM_004451 X
ERαHumanNM_000125 X
FXRHumanNM_005123 X
GRHumanNM_000176XX
LXRb-NCoR1Human  X
LXRαHumanNM_005693 X
LXRβHumanNM_007121.4 X
MRHumanNM_000901XX
PPARαHumanNM_001001930 X
PPARγHumanNM_138711 X
PPARδHumanNM_006238 X
PRαHumanNM_000926 X
PRβHumanNM_000926XX
RARαHumanNM_000964 X
RARβHumanNM_000965 X
RORgHumanNM_001001523 X
RXRαHumanNM_002957 X
RXRγHumanNM_002957 X
THRαHumanNM_199334 X
THRβHumanNM_000461 X