Services > Screening & Profiling

Screening and Profiling Services

With multiple assay formats to choose from, DiscoveRx’s custom profiling service provides a flexible approach for compound profiling. Our custom profiling service gives you the flexibility to choose any target from our broad selection. This is the ultimate solution if your interest lies in a specific area.  Choose from: any target in our portfolio, multiple assay readouts, agonist, antagonist, allosteric or inverse agonist and single point or dose response.

 
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Features & Benefits

  • Select any target in our portfolio
  • Flexible - multiple assay readouts
  • Average 20 day turnaround time
  • Extensive validation and appropriate controls included
  • Multiple compound types - agonist, antagonist, allosteric and inverse agonist
  • Choice of format - Single point or dose response


GPCRs

Choose from 3 different assay readouts: arrestin recruitment, second messenger signaling and receptor internalization. A majority of targets are available in two or three formats.


Kinases

Select from KINOMEscan’s panel of biochemical kinase assays or PathHunter cell-based assays for receptor tyrosine and cytosolic tyrosine kinase assays.


Nuclear Hormone Receptors

Chose from a comprehensive selection of cell-based assays available that interrogate NHR activity via nuclear translocation or steroid co-factor recruitment that minimizes off-target effects common with reporter gene approaches.


Pathway assays

DiscoveRx's pathway assay portfolio provides a selection of unique cell-based assays that measure a variety of cell activities involving cellular signaling and pathways.